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Just as that has been determined, there was a new twist this week: engineering bacteria to induce a potent T cell immune response to kill the tumor.
The control T cell and CAR T cell infusions were administered once a week after Day 7. Both the CAR T product and the control T cells relied on CRISPR gene editing to decrease expression of native T cell receptors.
The control T cell and CAR T cell infusions were administered once a week after Day 7. Both the CAR T product and the control T cells relied on CRISPR gene editing to decrease expression of native T cell receptors.
The control T cell and CAR T cell infusions were administered once a week after Day 7. Both the CAR T product and the control T cells relied on CRISPR gene editing to decrease expression of native T cell receptors.
The data also demonstrated anti-tumor activity, and in particular, durable responses, both of which continue to guide our plans to conduct a registration Phase 3 trial in relapsed peripheral T cell lymphoma.
The totality of our clinical data set shows significant improvements in tumor response and overall survival, coupled with highly correlated immunological responses measured by an improved T cell profile in the tumor microenvironment.